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カタログ番号	製品名	別名	ターゲット
T8464	RA-9		Apoptosis , DUB
	RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.		Apoptosis , DUB
T3102	NS-1619		Apoptosis , Potassium Channel
	NS1619 have cardio-protective effects after ischemia-reperfusion injury.		Apoptosis , Potassium Channel
T3713	BAY-876		transporter
	BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...		transporter
T16522	Phenoxodiol	Dehydroequol,Idronoxil,Haginin E	Apoptosis , IAP , Caspase , Topoisomerase , p53
	Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apop...		Apoptosis , IAP , Caspase , Topoisomerase , p53
T1841	UNC0379		Histone Methyltransferase
	UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.		Histone Methyltransferase
T24557	NSC756093	NSC-756093,NSC 756093	Others
	NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.		Others
T9698	UC2288		Mdm2 , p53
	UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.		Mdm2 , p53
T3082	SGC0946		Histone Methyltransferase
	SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.		Histone Methyltransferase
T6207	SC144		Apoptosis , Interleukin
	SC144 is an orally active small-molecule gp130 inhibitor.		Apoptosis , Interleukin
T9497	Niraparib tosylate monohyrate		PARP
	Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...		PARP
T21412	Ketorolac	Toradol,Sprix,Acuvail,Macril,Acular	COX
	Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.		COX
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T8930	CID44216842	KUC103479N-02	CDK , Ras
	CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...		CDK , Ras
T2679	BMS-265246	BMS265246	CDK
	BMS-265246 is a potent and selective CDK1/2 inhibitor.		CDK
T2463	ML141	CID-2950007	Apoptosis , CDK , Ras
	ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).		Apoptosis , CDK , Ras
T3231	Niraparib	MK-4827	Apoptosis , Others , PARP
	Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis.		Apoptosis , Others , PARP
T8806	Fluzoparib	HS10160,SHR3162	PARP
	Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.		PARP
T2617	SNS-314 Mesylate	SNS-314	Aurora Kinase
	SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor (IC50: 9/31/3 nM). It is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.		Aurora Kinase
T14871	Carboxyamidotriazole Orotate	L-651582 Orotate,CAI Orotate	Calcium Channel
	Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o...		Calcium Channel
T6646	Rosiglitazone hydrochloride	BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T6763	Xevinapant	ARRY-334543,SM-406,AT406,Debio-1143	IAP
	Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ...		IAP
T0964	Floxuridine	5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640	Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
	Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T4102	Goserelin acetate	Fertilan,ICI-118630 acetate,Zoladex	Apoptosis , GNRH Receptor
	Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.		Apoptosis , GNRH Receptor
T3353	Niraparib hydrochloride	MK-4827 hydrochloride,MK-4827 (hydrochloride)	Apoptosis , Others , PARP
	Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of...		Apoptosis , Others , PARP
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T6892	Niraparib tosylate	MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate	Apoptosis , PARP
	Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.		Apoptosis , PARP
T3299	Xevinapant hydrochloride	AT-406 HCl,SM-406	Apoptosis , IAP
	Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66....		Apoptosis , IAP
T72046	PF-17		Others
	PF-17 can be used as a PUF60 inhibitor for the treatment of ovarian cancer.		Others
T24997	ABT-510 acetate	ABT 510 acetate	Apoptosis
	ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...		Apoptosis
T17216	Valspodar	PSC 833	P-gp
	Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.		P-gp
T68065	Enloplatin
	Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.
TP2051L	CTCE 9908 acetate		CXCR
	CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.		CXCR
T34262	RAPTA-C		Apoptosis
	RAPTA-C induces EAC cell cycle arrest and apoptosis via the mitochondrial and p53-JNK pathways, and can be used in the study of breast and ovarian cancer.		Apoptosis
T13783	MT-4		Others
	MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.		Others
T17159	Treosulfan	NSC 39069,Treosulphan	DNA Alkylator/Crosslinker , DNA Alkylation
	Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.		DNA Alkylator/Crosslinker , DNA Alkylation
T12238	NNC 55-0396	NNC 55-0396 dihydrochloride	Calcium Channel
	NNC 55-0396 is a highly selective blocker of T-type calcium channel with IC50 of 6.8 μM. NNC 55-0396 can be used in studies about preventing human ovarian cancer cell proliferation.		Calcium Channel
T13572	Cancer-Targeting Compound 1		Others
	Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention of fibroids, uterine leiomyomas, polycystic ovarian syndrome, or hormone-dependent Cancer, among othe...		Others
T14510	BAY-850		Epigenetic Reader Domain
	BAY-850 is a selective and potent inhibitor of adenosine triphosphatase family protein 2 (ATAD2) (IC50: 166 nM) that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.		Epigenetic Reader Domain
T40199	Tulmimetostat	CPI-0209	Histone Methyltransferase
	Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced solid tumors.		Histone Methyltransferase
T20742	TG-89		FLT , c-RET , JAK
	TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer.		FLT , c-RET , JAK
T28935	TDRL-551		Others
	TDRL-551 is a novel and potent replication protein A (RPA) inhibitor (IC50=18 µM) with potential anticancer activity.TDRL-551 inhibits RPA-DNA interaction and enhances the efficacy of platinum-based chemotherapy for lung...		Others
T37376	PHY34		Autophagy
	PHY34 is a late stage autophagy inhibitor with nanomolar level inhibitory effect and anti-tumor activity against high-grade serous ovarian cancer (HGSOC) in vivo.		Autophagy
T76749	Zilovertamab	Cirmtuzumab,UC-961	Others
	Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to s...		Others
T16680	PTC-028		Apoptosis , BMI-1
	PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspas...		Apoptosis , BMI-1
T64167L	Ifebemtinib FA	BI-853520 FA（1227948-82-4 Free base)	FAK
	Ifebemtinib FA (BI-853520 FA) is an orally active and potent inhibitor of adhesion patch kinase (FAK) with anticancer and antiproliferative activity for the study of ovarian and lung cancer.		FAK
T67741	SU056		Others
	SU056 is a YB-1 inhibitor. SU056 interacts with YB-1 and inhibits and downstream proteins and pathways. SU056 can induce cell-cycle arrest, apoptosis, and inhibit cell migration in ovarian cancer cells.		Others
T60039	KSQ-4279	USP1-IN-1	PARP , DUB
	KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine and pancreatic ...		PARP , DUB
T77408	Abagovomab	ACA 125	Others
	Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal antibody that targets the tumor-associated antigen CA-125. Abagovomab is produced by hybridoma cells in mice. Abagovomab can be used to study ova...		Others
T10762	Ceranib1		Others
	Ceranib1 is an inhibitor of ceramidase. It inhibits the proliferation of ovarian cancer cells. Ceranib1 inhibits ceramidase activity toward an exogenous ceramide analog, induces the accumulation of multiple ceramide spec...		Others
T76766	Mirvetuximab	M9346A	Antifolate
	Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti...		Antifolate

Compounds

RA-9

T8464

Synonym:

Target: Apoptosis, DUB

NS-1619

T3102

Synonym:

Target: Apoptosis, Potassium Channel

Synonym: Dehydroequol,Idronoxil,Haginin E

Target: Apoptosis, IAP, Caspase, Topoisomerase, p53

UNC0379

T1841

Synonym:

Target: Histone Methyltransferase

NSC756093

T24557

Synonym: NSC-756093,NSC 756093

Target: Histone Methyltransferase

SC144

T6207

Synonym:

Target: Apoptosis, Interleukin

Niraparib tosylate monohyrate

Synonym: Toradol,Sprix,Acuvail,Macril,Acular

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

CID44216842

T8930

Synonym: KUC103479N-02

Target: Apoptosis, CDK, Ras

Niraparib

T3231

Synonym: MK-4827

Target: Apoptosis, Others, PARP

Fluzoparib

T8806

Synonym: HS10160,SHR3162

Target: Aurora Kinase

Carboxyamidotriazole Orotate

T14871

Synonym: L-651582 Orotate,CAI Orotate

Target: Calcium Channel

Rosiglitazone hydrochloride

T6646

Synonym: BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Xevinapant

T6763

Synonym: ARRY-334543,SM-406,AT406,Debio-1143

Target: IAP

Floxuridine

T0964

Synonym: 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV

Goserelin acetate

T4102

Synonym: Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

Niraparib hydrochloride

T3353

Synonym: MK-4827 hydrochloride,MK-4827 (hydrochloride)

Target: Apoptosis, Others, PARP

Minocycline hydrochloride

T1101

Synonym: Minocycline HCl

Target: HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Niraparib tosylate

T6892

Synonym: MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate

Target: Apoptosis, PARP

Xevinapant hydrochloride

T3299

Synonym: AT-406 HCl,SM-406

Target: Apoptosis, IAP

Synonym: ABT 510 acetate

Synonym: NSC 39069,Treosulphan

Target: DNA Alkylator/Crosslinker, DNA Alkylation

NNC 55-0396

T12238

Synonym: NNC 55-0396 dihydrochloride

Target: Calcium Channel

Cancer-Targeting Compound 1

Target: Epigenetic Reader Domain

Tulmimetostat

T40199

Synonym: CPI-0209

Target: Histone Methyltransferase

TG-89

T20742

Synonym:

Target: FLT, c-RET, JAK

Synonym: Cirmtuzumab,UC-961

Target: Apoptosis, BMI-1

Ifebemtinib FA

T64167L

Synonym: BI-853520 FA（1227948-82-4 Free base)

カタログ番号	製品名	別名	ターゲット
T5755	Aloesin		Tyrosinase
	Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin.		Tyrosinase
TN1839	Kumatakenin	Jaranol,Kaempferol 3,7-O-dimethyl ether	Apoptosis , Anti-infection
	Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.		Apoptosis , Anti-infection
T5S1882	Songorine	Napellonine,Zongorine,Bullatine G	Others , GABA Receptor
	Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.		Others , GABA Receptor
TN2064	Physcion 8-O-β-D-glucopyranoside	Physcion 8-O-beta-D-monoglucoside	TNF
	Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities. Physcion 8-O-β-D-glucopyranoside can be used in studies about common malignancy cancer.		TNF
T34394	Rotenolone	Rotenolone I,12alpha-HYDROXYROTENONE	Others
	Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus.		Others
T1174	Topotecan hydrochloride	SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl	Apoptosis , Topoisomerase , Autophagy
	Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.		Apoptosis , Topoisomerase , Autophagy
T3S1265	Liriopesides B	Nolinospiroside F	Others
	Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.		Others
T5784	Topotecan	NSC 609669,SKF 104864A	Topoisomerase , Autophagy
	Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.		Topoisomerase , Autophagy
T5780	HYPOCRELLIN B		Apoptosis , Parasite , Antifungal
	HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre...		Apoptosis , Parasite , Antifungal
T21883	Gedunin		HSP
	Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation.		HSP
T4S0998	Trifolirhizin		TNF , Tyrosinase
	Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ...		TNF , Tyrosinase
T35749	Thymohydroquinone	Thymoquinol	Antioxidant , Reactive Oxygen Species
	Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulate...		Antioxidant , Reactive Oxygen Species
T3923	Calycosin	Cyclosin,3'-Hydroxyformononetin	Apoptosis , Tyrosinase
	Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...		Apoptosis , Tyrosinase
T17155	Trabectedin	Ecteinascidin 743,ET-743	Apoptosis , Reactive Oxygen Species
	Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...		Apoptosis , Reactive Oxygen Species
TN4341	IVHD-valtrate		Mdm2 , BCL , PARP , Caspase , p53
	VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a basis for development of the compound as a novel chemothera...		Mdm2 , BCL , PARP , Caspase , p53
TN5156	Totaradiol		NADPH-oxidase
	Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line.		NADPH-oxidase
TN4154	Gomisin L1		Others
	(-)-Gomisin L1 induces G2/M arrest and apoptosis in human ovarian cancer cells.		Others
TN2229	Soyasaponin Ac		Others
	Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells.		Others
TN3383	α-Amyrin palmitate	alpha-Amyrin palmitate	PKA
	alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM), it also shows weak cytotoxicity against the ...		PKA
T36893	4-oxo Withaferin A
	4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
TN2913	3-Acetoxy-11-ursen-28,13-olide		Phosphatase
	3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A278...		Phosphatase
TN3447	Arjunglucoside I
	Arjunglucoside I has anti-inflammatory activity, it exhibits significant activity against carrageenan-induced paw edema in rat. It also shows antiproliferative activity against the A2780 human ovarian cancer cell line wi...
T83762	Lentztrehalose C
	Lentztrehalose C, a disaccharide identified in Lentzea, exhibits autophagy-inducing activity. It effectively induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells at a concentration of 100 mM.
TN2529	1-Decarboxy-3-oxo-ceanothic acid		DNA/RNA Synthesis
	1-Decarboxy-3-oxo-ceanothic acid shows in vitro cytotoxic activity in a human ovarian adenocarcinoma cell line, the cytotoxic effect is mediated, at least in part, by the induction of apoptosis. It shows cytotoxic agains...		DNA/RNA Synthesis
T35647	4-oxo-27-TBDMS Withaferin A
	4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
TN4168	Grifolin		Others
	Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proli...		Others
T37552	(+)-Macrosphelide A
	(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent man...
T38250	L-Sepiapterin
	L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
TN6524	Irilone
	Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 ...
TN2936	3-Hydroxy-11-ursen-28,13-olide		Others
	3β-Hydroxy-urs-11-en-28,13β-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line relative to silymarin as a reference standard. It exhibits weak-mod...		Others
TN5474	Bonducellin
	Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon...
T35409	(+)-δ-Cadinene		Apoptosis , Antibacterial
	(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 ...		Apoptosis , Antibacterial
TN3364	Agrimonolide		Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK
	Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ...		Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK

天然物製品

Synonym: Jaranol,Kaempferol 3,7-O-dimethyl ether

Target: Apoptosis, Anti-infection

Songorine

T5S1882

Synonym: Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Physcion 8-O-β-D-glucopyranoside

TN2064

Synonym: Physcion 8-O-beta-D-monoglucoside

Target: TNF

Rotenolone

T34394

Synonym: Rotenolone I,12alpha-HYDROXYROTENONE

Target: Others

Topotecan hydrochloride

T1174

Synonym: SKF 104864A,SKFS 104864A,NSC609699,Nogitecan HCl,NSC 609669,Topotecan HCl

Target: Apoptosis, Topoisomerase, Autophagy

Liriopesides B

T3S1265

Synonym: Nolinospiroside F

Target: Others

Topotecan

T5784

Synonym: NSC 609669,SKF 104864A

Target: Topoisomerase, Autophagy

HYPOCRELLIN B

T5780

Synonym:

Target: Apoptosis, Parasite, Antifungal

Target: TNF, Tyrosinase

Thymohydroquinone

T35749

Synonym: Thymoquinol

Target: Antioxidant, Reactive Oxygen Species

Calycosin

T3923

Synonym: Cyclosin,3'-Hydroxyformononetin

Target: Apoptosis, Tyrosinase

Trabectedin

T17155

Synonym: Ecteinascidin 743,ET-743

Target: Apoptosis, Reactive Oxygen Species

IVHD-valtrate

TN4341

Synonym:

Target: Mdm2, BCL, PARP, Caspase, p53

Totaradiol

TN5156

Synonym:

Target: NADPH-oxidase

Synonym: alpha-Amyrin palmitate

3-Acetoxy-11-ursen-28,13-olide

1-Decarboxy-3-oxo-ceanothic acid

TN2529

Synonym:

Target: DNA/RNA Synthesis

4-oxo-27-TBDMS Withaferin A

3-Hydroxy-11-ursen-28,13-olide

Target: Apoptosis, Antibacterial

Agrimonolide

TN3364

Synonym:

Target: Apoptosis, Dehydrogenase, p38 MAPK, ROS, JAK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01432	CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated	Human	HEK293 Cells
	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t...
TMPY-00117	FGF-16 Protein, Human, Cynomolgus, Recombinant	Human,Cynomolgus	Baculovirus Insect Cells
	Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-03979	ARHI Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types...
TMPK-00293	Nectin-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymp...
TMPY-00025	Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all majo...
TMPY-01299	GMF gamma/GMFG Protein, Human, Recombinant (His)	Human	E. coli
	The glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may mediate the pluripotentiality...
TMPK-00224	BTN3A2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a pote...
TMPK-00172	B7-H4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A solu...
TMPY-04387	AKT2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog...
TMPJ-01125	PEA15 Protein, Human, Recombinant	Human	E. coli
	Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis...
TMPY-01992	Kallikrein 8/KLK8 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka...
TMPY-00375	VMO1 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg white and preventing infection from...
TMPY-04780	VMO1 Protein, Human, Recombinant	Human	HEK293 Cells
	Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg white and preventing infection from...
TMPJ-00501	CLEC3B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind...
TMPY-02398	TLE3 Protein, Human, Recombinant (aa 484-772, GST)	Human	E. coli
	The association between high TLE3 expression and a favorable response to taxane-containing chemotherapy regimens was validated in patients with non-serous ovarian cancer. That TLE3 expression may serve as a marker of che...
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPY-04307	GNRH2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleav...
TMPY-01775	AIM2 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...

CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

TMPJ-01432

Species: Human

Expression System: HEK293 Cells

FGF-16 Protein, Human, Cynomolgus, Recombinant

TMPY-00117

Species: Human,Cynomolgus

Expression System: Baculovirus Insect Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

ARHI Protein, Human, Recombinant (mFc)

TMPY-03979

Species: Human

Expression System: HEK293 Cells

Nectin-2 Protein, Human, Recombinant (His & Avi)

TMPK-00293

Species: Human

Expression System: HEK293 Cells

Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc)

TMPY-00025

Species: Human

Expression System: HEK293 Cells

GMF gamma/GMFG Protein, Human, Recombinant (His)

TMPY-01299

Species: Human

Expression System: E. coli

BTN3A2 Protein, Human, Recombinant (His & Avi)

TMPK-00224

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Human, Recombinant (His & Avi)

TMPK-00172

Species: Human

Expression System: HEK293 Cells

AKT2 Protein, Human, Recombinant (His & GST)

TMPY-04387

Species: Human

Expression System: Baculovirus Insect Cells

PEA15 Protein, Human, Recombinant

TMPJ-01125

Species: Human

Expression System: E. coli

Kallikrein 8/KLK8 Protein, Human, Recombinant (His)

TMPY-01992

Species: Human

Expression System: HEK293 Cells

VMO1 Protein, Human, Recombinant (mFc)

TMPY-00375

Species: Human

Expression System: HEK293 Cells

VMO1 Protein, Human, Recombinant

TMPY-04780

Species: Human

Expression System: HEK293 Cells

CLEC3B Protein, Human, Recombinant (His)

TMPJ-00501

Species: Human

Expression System: HEK293 Cells

TLE3 Protein, Human, Recombinant (aa 484-772, GST)

TMPY-02398

Species: Human

Expression System: E. coli

RRM1 Protein, Human, Recombinant (His & GST)

TMPY-03287

Species: Human

Expression System: Baculovirus Insect Cells

GNRH2 Protein, Human, Recombinant (hFc)

TMPY-04307

Species: Human

Expression System: HEK293 Cells

AIM2 Protein, Human, Recombinant (GST)

TMPY-01775

Species: Human

Expression System: Baculovirus Insect Cells

Cathepsin V Protein, Human, Recombinant (His)

TMPY-01249

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L2196	Anti-Ovarian Cancer Compound Library	1867 compounds

L4600	Selected Plant-Sourced Compound Library	3048 compounds
	A unique collection of 3048 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-Ovarian Cancer Compound Library

L2196

Compounds: 1867

Selected Plant-Sourced Compound Library

L4600

Compounds: 3048